DE NOVO TRANSCRIPTOME ANALYSIS PROVIDES INSIGHTS INTO IMMUNE RELATED GENES AND THE RIG-I-LIKE RECEPTOR SIGNALING PATHWAY IN THE FRESHWATER PLANARIAN (DUGESIA JAPONICA).

BACKGROUND:The freshwater planarian Dugesia japonica (D.japonica) possesses extraordinary ability to regenerate lost organs or body parts.Interestingly, in the process of regeneration, there is little wound infection, suggesting that D.japonica has a formidable innate immune system.The importance of immune system prompted us to search for immune-re

Individuals with congenital amusia have a lifelong history of unreliable pitch processing.Accordingly, they downweight pitch cues during speech perception and instead rely on other dimensions such as duration.We investigated the neural basis for this strategy.During fMRI, individuals with amusia (N = 15) and controls Hall or Caged Light (N = 15) re

BackgroundInjury surveillance and workload monitoring are important aspects of professional sports, including cricket.However, at the community level, there is a dearth of accessible and intelligent surveillance tools.Mobile apps are an accessible tool for monitoring cricket-related injuries at all levels.ObjectiveThe objective of this paper is to

Numb was originally discovered as an intrinsic cell fate determinant in Drosophila by antagonizing Notch signaling.The present study is to characterize the role of Numb in oxidative stress-induced apoptosis of renal proximal tubular cells.Exposure of NRK52E cells to puromycin aminonucleoside (PA) resulted in caspase 3-dependent apoptosis.Numb expre

Probing the dynamic activities of protein kinases in real-time in living cells constitutes a major challenge that requires specific and sensitive tools tailored to meet the particular demands associated with cellular imaging.The development of genetically-encoded and synthetic fluorescent biosensors has provided means of monitoring protein kinase H